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BSORF Gene Entry : BG12583

ORF IDBG12583 (BSU29230)
Locationcomplement(2991269..2994616)  
Length1115 aa
3348 bp   +upstreambp   +downstreambp
Molecular mass125137
Isoelectric point6.02
GenednaE         Subtilist      dnaE         UniProt      O34623
ProductDNA polymerase III alpha subunit
EC number2.7.7.7
Motifpf:PHP 4 198
pf:DNA_pol3_alpha 228 704
pf:Trans_reg_C 427 498
pf:tRNA_anti 954 1031
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category3.1 : DNA replication  
KEGG pathway 
Purine metabolism

Pyrimidine metabolism

DNA replication

Mismatch repair

Homologous recombination

EssentialYes (Mutant)
Mutant
Northernno
BSTF
DNA array data BG12583
Reference
1. Barnes MH, Leo CJ, Brown NC (1998) DNA polymerase III of Gram-positive eubacteria is a zinc metalloprotein conserving an essential finger-like domain. Biochemistry 37:15254-60.[PMID:9799485]
2. Dervyn E, Suski C, Daniel R, Bruand C, Chapuis J, Errington J, Janniere L, Ehrlich SD (2001) Two essential DNA polymerases at the bacterial replication fork. Science 294:1716-9.[PMID:11721055]
PubMed search

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