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BSORF Gene Entry : BG12347

ORF IDBG12347 (BSU31520)
Location3237157..3238758  
Length533 aa
1602 bp   +upstreambp   +downstreambp
Molecular mass58759.5
Isoelectric point6.95
GeneyufL         Subtilist      yufL         UniProt      
Producttwo-component sensor histidine kinase. cognate response regulator is YufM. malate uptake and metabolism.
EC number2.7.13.3
Motifpf:SMP_2 1 220
pf:PAS 212 313
pf:PAS_4 218 318
pf:HATPase_c 419 526
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category1.3 : Sensors (signal transduction)  
KEGG pathway 
Two-component system

EssentialNo (Mutant)
MutantBFS1431
Northernno
BSTF
DNA array data BG12347
Reference
1. Tanaka K, Kobayashi K, Ogasawara N (2003) The Bacillus subtilis YufLM two-component system regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Microbiology 149:2317-29.[PMID:12949159]
2. Doan T, Servant P, Tojo S, Yamaguchi H, Lerondel G, Yoshida K, Fujita Y, Aymerich S (2003) The Bacillus subtilis ywkA gene encodes a malic enzyme and its transcription is activated by the YufL/YufM two-component system in response to malate. Microbiology 149:2331-43.[PMID:12949160]
PubMed search

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