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BSORF Gene Entry : BG10794

ORF IDBG10794 (BSU21820)
Locationcomplement(2297106..2297900)  
Length264 aa
795 bp   +upstreambp   +downstreambp
Molecular mass30387.3
Isoelectric point6.27
GenethyB         Subtilist      thyB         UniProt      P11044
Productthymidylate synthase B
EC number2.1.1.45
Motifpf:Thymidylat_synt 2 264
ps:THYMIDYLATE_SYNTHASE 126
ps:THYMIDYLATE_SYNTHASE 127
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category2.3 : Metabolism of nucleotides and nucleic acids  
KEGG pathway 
Pyrimidine metabolism

One carbon pool by folate

EssentialNo (Reference)
Mutant
Northernno
BSTF
DNA array data BG10794
Reference
1. Montorsi M, Lorenzetti R (1993) Heat-stable and heat-labile thymidylate synthases B of Bacillus subtilis: comparison of the nucleotide and amino acid sequences. Mol Gen Genet 239:1-5.[PMID:8510640]
2. Tam NH, Borriss R (1998) Genes encoding thymidylate synthases A and B in the genus Bacillus are members of two distinct families. Mol Gen Genet 258:427-30.[PMID:9648749]
3. Stout TJ, Schellenberger U, Santi DV, Stroud RM (1998) Crystal structures of a unique thermal-stable thymidylate synthase from Bacillus subtilis. Biochemistry 37:14736-47.[PMID:9778348]
PubMed search

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