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BSORF Gene Entry : BG10765

ORF IDBG10765 (BSU24220)
Locationcomplement(2518023..2518826)  
Length267 aa
804 bp   +upstreambp   +downstreambp
Molecular mass29540.2
Isoelectric point5.99
Genespo0A         Subtilist      spo0A         UniProt      P06534
Synonymspo0C,spo0G,spoIIL,sof-1
Producttwo-component response regulator central for the initiation of sporulation
EC number
Motifpf:Response_reg 6 120
pf:Spo0A_C 152 267
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category3.4.2 : Regulation  
KEGG pathway 
Two-component system

EssentialNo (Reference)
Mutant
Northernyes
BSTFBG10765
DNA array data BG10765
Reference
1. Kudoh J, Ikeuchi T, Kurahashi K (1985) Nucleotide sequences of the sporulation gene spo0A and its mutant genes of Bacillus subtilis. Proc Natl Acad Sci U S A 82:2665-8.[PMID:3921963]
2. Rowe-Magnus DA, Spiegelman GB (1998) DNA strand separation during activation of a developmental promoter by the Bacillus subtilis response regulator Spo0A. Proc Natl Acad Sci U S A 95:5305-10.[PMID:9560271]
3. Buckner CM, Schyns G, Moran CP Jr (1998) A region in the Bacillus subtilis transcription factor Spo0A that is important for spoIIG promoter activation. J Bacteriol 180:3578-83.[PMID:9658000]
4. Hatt JK, Youngman P (1998) Spo0A mutants of Bacillus subtilis with sigma factor-specific defects in transcription activation. J Bacteriol 180:3584-91.[PMID:9658001]
5. Rowe-Magnus DA, Mencia M, Rojo F, Salas M, Spiegelman GB (1998) Transcriptional activation of the Bacillus subtilis spoIIG promoter by the response regulator Spo0A is independent of the C-terminal domain of the RNA polymerase alpha subunit. J Bacteriol 180:4760-3.[PMID:9721325]
6. Rowe-Magnus DA, Spiegelman GB (1998) Contributions of the domains of the Bacillus subtilis response regulator Spo0A to transcription stimulation of the spoIIG operon. J Biol Chem 273:25818-24.[PMID:9748255]
7. Cervin MA, Spiegelman GB (1999) The Spo0A sof mutations reveal regions of the regulatory domain that interact with a sensor kinase and RNA polymerase. Mol Microbiol 31:597-607.[PMID:10027976]
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