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BSORF Gene Entry : BG10732

ORF IDBG10732 (BSU01430)
Location148931..149875  
Length314 aa
945 bp   +upstreambp   +downstreambp
Molecular mass34644.8
Isoelectric point4.59
GenerpoA         Subtilist      rpoA         UniProt      P20429
ProductDNA-directed RNA polymerase alpha chain
EC number2.7.7.6
Motifpf:RNA_pol_L 17 226
pf:RNA_pol_A_bac 56 171
pf:RNA_pol_A_CTD 238 305
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category3.4.3 : Elongation  
KEGG pathway 
Purine metabolism

Pyrimidine metabolism

RNA polymerase

EssentialYes (Speculation)
Mutant
Northernno
BSTF
DNA array data BG10732
Reference
1. Boylan SA, Suh JW, Thomas SM, Price CW (1989) Gene encoding the alpha core subunit of Bacillus subtilis RNA polymerase is cotranscribed with the genes for initiation factor 1 and ribosomal proteins B, S13, S11, and L17. J Bacteriol 171:2553-62.[PMID:2496109]
2. Mencia M, Monsalve M, Rojo F, Salas M (1998) Substitution of the C-terminal domain of the Escherichia coli RNA polymerase alpha subunit by that from Bacillus subtilis makes the enzyme responsive to a Bacillus subtilis transcriptional activator. J Mol Biol 275:177-85.[PMID:9466901]
3. Rojo F, Mencia M, Monsalve M, Salas M (1998) Transcription activation and repression by interaction of a regulator with the alpha subunit of RNA polymerase: the model of phage phi 29 protein p4. Prog Nucleic Acid Res Mol Biol 60:29-46.[PMID:9594570]
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