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BSORF Gene Entry : BG10712

ORF IDBG10712 (BSU15470)
Location1618304..1618849  
Length181 aa
546 bp   +upstreambp   +downstreambp
Molecular mass20118.8
Isoelectric point4.99
GenepyrR         Subtilist      pyrR         UniProt      P39765
Producttranscriptional attenuator of the pyrimidine operon / uracil phosphoribosyltransferase
EC number2.4.2.9
Motifpf:Pribosyltran 4 136
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category3.4.2 : Regulation  
KEGG pathway 
Pyrimidine metabolism

EssentialNo (Mutant)
MutantBFS2815
Northernno
BSTFBG10712
DNA array data BG10712
Reference
1. Turner RJ, Lu Y, Switzer RL (1994) Regulation of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster by an autogenous transcriptional attenuation mechanism. J Bacteriol 176:3708-22.[PMID:8206849]
2. Turner RJ, Bonner ER, Grabner GK, Switzer RL (1998) Purification and characterization of Bacillus subtilis PyrR, a bifunctional pyr mRNA-binding attenuation protein/uracil phosphoribosyltransferase. J Biol Chem 273:5932-8.[PMID:9488732]
3. Tomchick DR, Turner RJ, Switzer RL, Smith JL (1998) Adaptation of an enzyme to regulatory function: structure of Bacillus subtilis PyrR, a pyr RNA-binding attenuation protein and uracil phosphoribosyltransferase. Structure 6:337-50.[PMID:9551555]
4. Switzer RL, Turner RJ, Lu Y (1999) Regulation of the Bacillus subtilis pyrimidine biosynthetic operon by transcriptional attenuation: control of gene expression by an mRNA-binding protein. Prog Nucleic Acid Res Mol Biol 62:329-67.[PMID:9932459]
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