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BSORF Gene Entry : BG10464

ORF IDBG10464 (BSU09950)
Locationcomplement(1070364..1071242)  
Length292 aa
879 bp   +upstreambp   +downstreambp
Molecular mass32356.1
Isoelectric point9.12
GeneprsA         Subtilist      prsA         UniProt      P24327
Productpric/parvulin family of rotamase
EC number5.2.1.8
Motifpf:Entericidin 1 27
pf:Mlp 1 175
pf:VirB 1 39
pf:FKBP_N 14 123
pf:Rotamase 141 224
ps:PPIC_PPIASE_1 163
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category1.6 : Protein secretion  
KEGG pathway 
EssentialYes (Mutant)
MutantPRSAp
Northernno
BSTF
DNA array data BG10464
Reference
1. Kontinen VP, Saris P, Sarvas M (1991) A gene (prsA) of Bacillus subtilis involved in a novel, late stage of protein export. Mol Microbiol 5:1273-83.[PMID:1956302]
2. Wu SC, Ye R, Wu XC, Ng SC, Wong SL (1998) Enhanced secretory production of a single-chain antibody fragment from Bacillus subtilis by coproduction of molecular chaperones. J Bacteriol 180:2830-5.[PMID:9603868]
3. Hyyrylainen HL, Vitikainen M, Thwaite J, Wu H, Sarvas M, Harwood CR, Kontinen VP, Stephenson K (2000) D-Alanine substitution of teichoic acids as a modulator of protein folding and stability at the cytoplasmic membrane/cell wall interface of Bacillus subtilis. J Biol Chem 275:26696-703.[PMID:10871614]
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