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BSORF Gene Entry : BG10337

ORF IDBG10337 (BSU27920)
Locationcomplement(2852661..2853947)  
Length428 aa
1287 bp   +upstreambp   +downstreambp
Molecular mass47526
Isoelectric point4.86
Geneobg         Subtilist      obg         UniProt      P20964
ProductGTP binding protein eesential for cell growth
EC number
Motifpf:GTP1_OBG 2 157
pf:GTP_EFTU 156 330
pf:Ras 156 330
pf:MMR_HSR1 159 285
pf:Miro 161 285
pf:ATP_bind_1 163 330
pf:Arf 174 328
pf:DUF1967 358 426
ps:GTP1_OBG 212
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category1.11 : General function prediction  
KEGG pathway 
EssentialYes (Mutant)
Mutant
Northernno
BSTF
DNA array data BG10337
Reference
1. Kok J, Trach KA, Hoch JA (1994) Effects on Bacillus subtilis of a conditional lethal mutation in the essential GTP-binding protein Obg. J Bacteriol 176:7155-60.[PMID:7961486]
2. Arigoni F, Talabot F, Peitsch M, Edgerton MD, Meldrum E, Allet E, Fish R, Jamotte T, Curchod ML, Loferer H (1998) A genome-based approach for the identification of essential bacterial genes. Nat Biotechnol 16:851-6.[PMID:9743119]
3. Scott JM, Ju J, Mitchell T, Haldenwang WG (2000) The Bacillus subtilis GTP binding protein obg and regulators of the sigma(B) stress response transcription factor cofractionate with ribosomes. J Bacteriol 182:2771-7.[PMID:10781545]
4. Morimoto T, Loh PC, Hirai T, Asai K, Kobayashi K, Moriya S, Ogasawara N (2002) Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis. Microbiology 148:3539-52.[PMID:12427945]
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