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BSORF Gene Entry : BG10304

ORF IDBG10304 (BSU24020)
Location2495898..2496734  
Length278 aa
837 bp   +upstreambp   +downstreambp
Molecular mass32430
Isoelectric point5.19
GenebmrR         Subtilist      bmrR         UniProt      P39075
Synonymbmr1R
Producttranscriptional activator of the bmrUR operon
EC number
Motifpf:MerR 7 45
pf:MerR-DNA-bind 50 108
pf:AraC_E_bind 130 277
ps:HTH_MERR_1 9
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category3.4.2 : Regulation  
KEGG pathway 
EssentialNo (Reference)
Mutant
Northernyes
BSTFBG10304
DNA array data BG10304
Reference
1. Ahmed M, Borsch CM, Taylor SS, Vazquez-Laslop N, Neyfakh AA (1994) A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates. J Biol Chem 269:28506-13.[PMID:7961792]
2. Zheleznova EE, Markham PN, Neyfakh AA, Brennan RG (1999) Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. Cell 96:353-62.[PMID:10025401]
3. Heldwein EE, Brennan RG (2001) Crystal structure of the transcription activator BmrR bound to DNA and a drug. Nature 409:378-82.[PMID:11201751]
PubMed search

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