move left ORF move right ORF

BSORF Gene Entry : BG10168

ORF IDBG10168 (BSU03480)
Location376968..387731  
Length3587 aa
10764 bp   +upstreambp   +downstreambp
Molecular mass401682
Isoelectric point4.87
GenesrfAA         Subtilist      srfAA         UniProt      P27206
SynonymcomL,srfA1,srfA
Productsurfactin synthetase subunit 1
EC number
Motifpf:Condensation 2 303
pf:Chaperone_III 368 479
pf:DUF137 473 578
pf:AMP-binding 488 891
pf:PP-binding 978 1042
pf:Condensation 1058 1344
pf:AMP-binding 1530 1930
pf:PP-binding 2015 2079
pf:Transferase 2080 2503
pf:Condensation 2095 2384
pf:AATase 2107 2507
pf:AMP-binding 2570 2963
pf:PP-binding 3046 3109
pf:Condensation 3122 3426
ps:AMP_BINDING 604
ps:AMP_BINDING 1651
ps:AMP_BINDING 2697
ps:PHOSPHOPANTETHEINE 1001
ps:PHOSPHOPANTETHEINE 3069
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category4.3 : Antibiotic production  
KEGG pathway 
Nonribosomal peptide structures

EssentialNo (Reference)
Mutant
Northernno
BSTF
DNA array data BG10168
Reference
1. Nakano MM, Magnuson R, Myers A, Curry J, Grossman AD, Zuber P (1991) srfA is an operon required for surfactin production, competence development, and efficient sporulation in Bacillus subtilis. J Bacteriol 173:1770-8.[PMID:1847909]
2. Cosby WM, Vollenbroich D, Lee OH, Zuber P (1998) Altered srf expression in Bacillus subtilis resulting from changes in culture pH is dependent on the Spo0K oligopeptide permease and the ComQX system of extracellular control. J Bacteriol 180:1438-45.[PMID:9515911]
3. Schneider A, Stachelhaus T, Marahiel MA (1998) Targeted alteration of the substrate specificity of peptide synthetases by rational module swapping. Mol Gen Genet 257:308-18.[PMID:9520265]
4. Guenzi E, Galli G, Grgurina I, Pace E, Ferranti P, Grandi G (1998) Coordinate transcription and physical linkage of domains in surfactin synthetase are not essential for proper assembly and activity of the multienzyme complex. J Biol Chem 273:14403-10.[PMID:9603952]
PubMed search

move left ORF move right ORF

[ BSORF | GenomeNet ]