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BSORF Gene Entry : BG10014

ORF IDBG10014 (BSU40550)
Location4168204..4169133  
Length309 aa
930 bp   +upstreambp   +downstreambp
Molecular mass33834.4
Isoelectric point4.51
GeneppaC         Subtilist      ppaC         UniProt      P37487
SynonymyybQ
Productinorganic pyrophosphatase
EC number3.6.1.1
Motifpf:DHH 1 147
pf:DHHA2 181 307
LocalizationPSORT  SOSUI
Ortholog SSDB     COG
Paralog SSDB
Homology FASTA-sp   BLAST-nr
3D Structure PDB     GTOP
Category2.6 : Metabolism of phosphate  
KEGG pathway 
Oxidative phosphorylation

EssentialYes (Mutant)
MutantYYBQp
Northernyes
BSTF
DNA array data BG10014
Reference
1. Aravind L, Koonin EV (1998) A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Trends Biochem Sci 23:17-9.[PMID:9478130]
2. Kuhn NJ, Ward S (1998) Purification, properties, and multiple forms of a manganese-activated inorganic pyrophosphatase from Bacillus subtilis. Arch Biochem Biophys 354:47-56.[PMID:9633597]
3. Young TW, Kuhn NJ, Wadeson A, Ward S, Burges D, Cooke GD (1998) Bacillus subtilis ORF yybQ encodes a manganese-dependent inorganic pyrophosphatase with distinctive properties: the first of a new class of soluble pyrophosphatase? Microbiology 144 ( Pt 9):2563-71.[PMID:9782505]
4. Shintani T, Uchiumi T, Yonezawa T, Salminen A, Baykov AA, Lahti R, Hachimori A (1998) Cloning and expression of a unique inorganic pyrophosphatase from Bacillus subtilis: evidence for a new family of enzymes. FEBS Lett 439:263-6.[PMID:9845334]
5. Parfenyev AN, Salminen A, Halonen P, Hachimori A, Baykov AA, Lahti R (2001) Quaternary structure and metal ion requirement of family II pyrophosphatases from Bacillus subtilis, Streptococcus gordonii, and Streptococcus mutans. J Biol Chem 276:24511-8.[PMID:11342544]
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