BSTF Data for BG14131

Classtwo comp regulator
FamilyresD like C-terminal DNA-binding motif
Family description
Mutant/Isogenic strainBFS2461(2)
SensorCssS (=YvqB)
Target geneshtrA, htrB, cssS, cssR (1)
cis Sequencenot
CommentHeat and secretion stress induces CssR-targets (1). The Css system is required to degrade misfolded exported proteins at the membrane-cell wall interface (2). DNA microarray analysis (3).
1. Hyyrylainen HL, Bolhuis A, Darmon E, Muukkonen L, Koski P, Vitikainen M, Sarvas M, Pragai Z, Bron S, van Dijl JM, (2001) A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress. Mol Microbiol 41:1159-72.[PMID:11555295]
2. Darmon E, Noone D, Masson A, Bron S, Kuipers OP, Devine KM, van Dijl JM (2002) A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis. J Bacteriol 184:5661-71.[PMID:12270824]
3. Kobayashi K, Ogura M, Yamaguchi H, Yoshida K, Ogasawara N, Tanaka T, Fujita Y (2001) Comprehensive DNA microarray analysis of Bacillus subtilis two-component regulatory systems. J Bacteriol 183:7365-70.[PMID:11717295]
PubMed search
Ortholog SSDB     COG
Paralog SSDB
Motif SSDB
Localization PSORT   SOSUI