BSTF Data for BG12056

Family description
Mutant/Isogenic strainFC1/168(1)
Target geneslrpC (3)
cis Sequencecurved region(2). LrpC orms stable complexes with curved sequences containing phased A tracts and wraps DNA to form spherical, nucleosome-like structures (4).
CommentE. coli Lrp homolog (1).
1. Beloin C, Ayora S, Exley R, Hirschbein L, Ogasawara N, Kasahara Y, Alonso JC, Hegarat FL (1997) Characterization of an lrp-like (lrpC) gene from Bacillus subtilis. Mol Gen Genet 256:63-71. [PMID:9341680]
2. Tapias A, Lopez G, Ayora S (2000) Bacillus subtilis LrpC is a sequence-independent DNA-binding and DNA-bending protein which bridges DNA. Nucleic Acids Res 28:552-9. [PMID:10606655]
3. Beloin C, Exley R, Mahe AL, Zouine M, Cubasch S, Le Hegarat F (2000) Characterization of LrpC DNA-binding properties and regulation of Bacillus subtilis lrpC gene expression. J Bacteriol 182:4414-24. [PMID:10913073]
4. Beloin C, Jeusset J, Revet B, Mirambeau G, Le Hegarat F, Le Cam E (2003) Contribution of DNA conformation and topology in right-handed DNA wrapping by the Bacillus subtilis LrpC protein. J Biol Chem 278:5333-42. [PMID:12458218]
PubMed search
Ortholog SSDB     COG
Paralog SSDB
Motif SSDB
Localization PSORT   SOSUI