BSTF Data for BG10765

Classtwo comp regulator
Family description
Mutant/Isogenic strainJH703(1)
SensorKinA,B (8),KinC (4),KinD,E(7)
Target genesabrB (2), kinA, spo0F, spo0A, spoIIA, spoIIE, spoIIG (8), ftsAZ(3), yjcP, yneE, ybcOPQST-ybdAB(9).
cis SequenceTGNCGAA(8)
CommentDNA microarray analysis (5).Processing of the Phr precursor proteins into the active pentapeptide form is a key event in the initiation of sporulation (6).
1. Ferrari FA, Trach K, LeCoq D, Spence J, Ferrari E, Hoch JA (1985) Characterization of the spo0A locus and its deduced product. Proc Natl Acad Sci U S A 82:2647-51. [PMID:3157992]
2. Strauch M, Webb V, Spiegelman G, Hoch JA (1990) The SpoOA protein of Bacillus subtilis is a repressor of the abrB gene. Proc Natl Acad Sci U S A 87:1801-5. [PMID:2106683]
3. Gonzy-Treboul G, Karmazyn-Campelli C, Stragier P (1992) Developmental regulation of transcription of the Bacillus subtilis ftsAZ operon. J Mol Biol 224:967-79. [PMID:1569582]
4. LeDeaux JR, Grossman AD (1995) Isolation and characterization of kinC, a gene that encodes a sensor kinase homologous to the sporulation sensor kinases KinA and KinB in Bacillus subtilis. J Bacteriol 177:166-75. [PMID:8002614]
5. Fawcett P, Eichenberger P, Losick R, Youngman P (2000) The transcriptional profile of early to middle sporulation in Bacillus subtilis. Proc Natl Acad Sci U S A 97:8063-8. [PMID:10869437]
6. Stephenson S, Mueller C, Jiang M, Perego M (2003) Molecular analysis of Phr peptide processing in Bacillus subtilis. J Bacteriol 185:4861-71. [PMID:12897006]
7. Jiang M, Shao W, Perego M, Hoch JA (2000) Multiple histidine kinases regulate entry into stationary phase and sporulation in Bacillus subtilis. Mol Microbiol 38:535-42. [PMID:11069677]
8. Hoch J (1993) spo0 genes, the phosphorelay, and the initiation of sporlation, p.747-755. In Sonenshein AL, Hoch, JA, Losick, R (ed), Bacillus subtilis and its related bacteria, American Sciety for Microbiology, Washington, DC. [PMID:A0002]
9. Piggot PJ, Losick R (2002) Sporulation genes and intercompartmental regulation. In Sonenshein AL, Hoch JA Losick R, Bacillus subtilis and its closest relatives, American Society for Microbiology, Washington, DC. [PMID:A0003]
PubMed search
Ortholog SSDB     COG
Paralog SSDB
Motif SSDB
Localization PSORT   SOSUI