BSTF Data for BG10593

ClassRNA binding regulator
Family descriptionBglG antiterminator motif
Mutant/Isogenic strainQB39(2)
Target genessacPA(1)
cis SequenceRAT(2,3,4)
Ligandsucrose in medium (1,2). SacT phosphorylation (2)
CommentSacT requires both enzyme I and HPr of the phosphotransferase system (PTS) for antitermination(2). SacT purification and reconstitution of transcription antitermination (4).
1. Debarbouille M, Arnaud M, Fouet A, Klier A, Rapoport G (1990) The sacT gene regulating the sacPA operon in Bacillus subtilis shares strong homology with transcriptional antiterminators. J Bacteriol 172:3966-73. [PMID:2163394]
2. Arnaud M, Vary P, Zagorec M, Klier A, Debarbouille M, Postma P, Rapoport G (1992) Regulation of the sacPA operon of Bacillus subtilis: identification of phosphotransferase system components involved in SacT activity. J Bacteriol 174:3161-70. [PMID:1577686]
3. Aymerich S, Steinmetz M (1992) Specificity determinants and structural features in the RNA target of the bacterial antiterminator proteins of the BglG/SacY family. Proc Natl Acad Sci U S A 89:10410-4. [PMID:1279678]
4. Arnaud M, Debarbouille M, Rapoport G, Saier MH Jr, Reizer J (1996) In vitro reconstitution of transcriptional antitermination by the SacT and SacY proteins of Bacillus subtilis. J Biol Chem 271:18966-72. [PMID:8702561]
PubMed search
Ortholog SSDB     COG
Paralog SSDB
Motif SSDB
Localization PSORT   SOSUI