BSTF Data for BG10376


ORF IDBG10376
SynonymccpA,graR,alsA
ClassHTH
FamilylacI
Family descriptionperiplasmic binding protein like motif
Mutant/Isogenic strain1A147/1A250 (1), SWV247/168(4), WLN-29/1A9(BGSC) (5)
Sensor
Target genesgntR, iolB, hutP, msmX, amyE, acoA, treP, citM, ackA, xylA, yjmA, yxjC, bglP, yobO, treP, araB, lcfA, kdgA,, ydbH, galT, ydhO, dra, yxkJ, xynB, acsA,acuABC, iolA, xynB, araA, araE, levD, acoR, etc.(2,6,7,8), rbs(9)
cis SequenceWTGNAANCGNWNNCW(2), WTGAAARCGYTTWW(8)
Ligandrapidly-metabolized carbohydrates(corepressor and coactivator in medium), P-ser-HPr(corepressor and coactivator in cell) (3)
CommentDNA microarray data (6,7)
Reference
1. Miwa Y, Saikawa M, Fujita Y (1994) Possible function and some properties of the CcpA protein of Bacillus subtilis. Microbiology 140 ( Pt 10):2567-75. [PMID:8000527]
2. Miwa Y, Nakata A, Ogiwara A, Yamamoto M, Fujita Y (2000) Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis. Nucleic Acids Res 28:1206-10. [PMID:10666464]
3. Fujita Y, Miwa Y, Galinier A, Deutscher J (1995) Specific recognition of the Bacillus subtilis gnt cis-acting catabolite-responsive element by a protein complex formed between CcpA and seryl-phosphorylated HPr. Mol Microbiol 17:953-60. [PMID:8596444]
4. Strauch MA (1995) AbrB modulates expression and catabolite repression of a Bacillus subtilis ribose transport operon. J Bacteriol 177:6727-31. [PMID:7592460]
5. Henkin TM, Grundy FJ, Nicholson WL, Chambliss GH (1991) Catabolite repression of alpha-amylase gene expression in Bacillus subtilis involves a trans-acting gene product homologous to the Escherichia coli lacl and galR repressors. Mol Microbiol 5:575-84. [PMID:1904524]
6. Yoshida K, Kobayashi K, Miwa Y, Kang CM, Matsunaga M, Yamaguchi H, Tojo S, Yamamoto M, Nishi R, Ogasawara N, et.al. (2001) Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis. Nucleic Acids Res 29:683-92. [PMID:11160890]
7. Moreno MS, Schneider BL, Maile RR, Weyler W, Saier MH Jr (2001) Catabolite repression mediated by the CcpA protein in Bacillus subtilis: novel modes of regulation revealed by whole-genome analyses. Mol Microbiol 39:1366-81. [PMID:11251851]
8. Miwa Y, Fujita Y (2001) Involvement of two distinct catabolite-responsive elements in catabolite repression of the Bacillus subtilis myo-inositol (iol) operon. J Bacteriol 183:5877-84. [PMID:11566986]
9. Strauch MA (1995) AbrB modulates expression and catabolite repression of a Bacillus subtilis ribose transport operon. J Bacteriol 177:6727-31. [PMID:7592460]
PubMed search
Ortholog SSDB     COG
Paralog SSDB
Motif SSDB
Localization PSORT   SOSUI