BSTF Data for BG10355


ORF IDBG10355
SynonymgerE
ClassHTH
FamilyluxR
Family description
Mutant/Isogenic strain522.2/SG38(1)
Sensor
Target genescotD,cotB,CotC,cotVWXYZ,sigK(1),cotG(3),cgeAB(4),cgeCDE(4), cotX(6), cwlH (7), ydhD, ykvP (9), ftsY (10), cotP(=ydfT)(12)
cis SequenceRWWTRGGYNNYY(1)
Ligandnot
CommentGerE crystallized (3,11). The rising level of GerE and the falling level of SpoIIID dictates the timing and level of spore coat protein synthesis (8). The DNA binding and promoter activation domeins of GerE (13, 14).
Reference
1. Ichikawa H, Halberg R, Kroos L (1999) Negative regulation by the Bacillus subtilis GerE protein. J Biol Chem 274:8322-7. [PMID:10075739]
2. Zheng L, Halberg R, Roels S, Ichikawa H, Kroos L, Losick R (1992) Sporulation regulatory protein GerE from Bacillus subtilis binds to and can activate or repress transcription from promoters for mother-cell-specific genes. J Mol Biol 226:1037-50. [PMID:1518043]
3. Sacco M, Ricca E, Losick R, Cutting S (1995) An additional GerE-controlled gene encoding an abundant spore coat protein from Bacillus subtilis. J Bacteriol 177:372-7. [PMID:7814326]
4. Roels S, Losick R (1995) Adjacent and divergently oriented operons under the control of the sporulation regulatory protein GerE in Bacillus subtilis. J Bacteriol 177:6263-75. [PMID:7592393]
5. Ducros VM, Brannigan JA, Lewis RJ, Wilkinson AJ (1998) Bacillus subtilis regulatory protein GerE. Acta Crystallogr D Biol Crystallogr 54:1453-5. [PMID:10089536]
6. Wade KH, Schyns G, Opdyke JA, Moran CP Jr (1999) A region of sigmaK involved in promoter activation by GerE in Bacillus subtilis. J Bacteriol 181:4365-73. [PMID:10400595]
7. Nugroho FA, Yamamoto H, Kobayashi Y, Sekiguchi J (1999) Characterization of a new sigma-K-dependent peptidoglycan hydrolase gene that plays a role in Bacillus subtilis mother cell lysis. J Bacteriol 181:6230-7. [PMID:10515909]
8. Ichikawa H, Kroos L (2000) Combined action of two transcription factors regulates genes encoding spore coat proteins of Bacillus subtilis. J Biol Chem 275:13849-55. [PMID:10788508]
9. Kodama T, Takamatsu H, Asai K, Ogasawara N, Sadaie Y, Watabe K (2000) Synthesis and characterization of the spore proteins of Bacillus subtilis YdhD, YkuD, and YkvP, which carry a motif conserved among cell wall binding proteins. J Biochem (Tokyo) 128:655-63. [PMID:11011148]
10. Kakeshita H, Oguro A, Amikura R, Nakamura K, Yamane K (2000) Expression of the ftsY gene, encoding a homologue of the alpha subunit of mammalian signal recognition particle receptor, is controlled by different promoters in vegetative and sporulating cells of Bacillus subtilis. Microbiology 146 ( Pt 10):2595-603. [PMID:11021934]
11. Ducros VM, Lewis RJ, Verma CS, Dodson EJ, Leonard G, Turkenburg JP, Murshudov GN, Wilkinson AJ, Brannigan JA (2001) Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis. J Mol Biol 306:759-71. [PMID:11243786]
12. Reischl S, Thake S, Homuth G, Schumann W (2001) Transcriptional analysis of three Bacillus subtilis genes coding for proteins with the alpha-crystallin domain characteristic of small heat shock proteins. FEMS Microbiol Lett 194:99-103. [PMID:11150673]
13. Crater DL, Moran CP Jr (2001) Identification of a DNA binding region in GerE from Bacillus subtilis. J Bacteriol 183:4183-9. [PMID:11418558]
14. Crater DL, Moran CP Jr (2002) Two regions of GerE required for promoter activation in Bacillus subtilis. J Bacteriol 184:241-9. [PMID:11741866]
PubMed search
Ortholog SSDB     COG
Paralog SSDB
Motif SSDB
Localization PSORT   SOSUI