BSTF Data for BG10185


ORF IDBG10185
SynonymglpP
ClassRNA binding regulator
Family
Family description
Mutant/Isogenic strainLUG0402(3)
Sensor
Target genesglpP(1), glpFK, glpD(1,2), glpTQ(1)
cis SequenceRAT(2,3)
Ligandglycerol-3-P in medium (2) and in cell (4)
CommentGlpP is also involved in glucose repression of glpD (2), which is mediated by phosphorylation of GlpK (4). Pure GlpP binds to glpD leader mRNA in vitro (gel shift experiments)(3).
Reference
1. Rutberg B (1997) Antitermination of transcription of catabolic operons. Mol Microbiol 23:413-21.[PMID:9044276]
2. Glatz E, Nilsson RP, Rutberg L, Rutberg B (1996) A dual role for the Bacillus subtilis glpD leader and the GlpP protein in the regulated expression of glpD: antitermination and control of mRNA stability. Mol Microbiol 19:319-28.[PMID:8825777]
3. Glatz E, Persson M, Rutberg B (1998) Antiterminator protein GlpP of Bacillus subtilis binds to glpD leader mRNA. Microbiology 144 ( Pt 2):449-56.[PMID:9493382]
4. Darbon E, Servant P, Poncet S, Deutscher J (2002) Antitermination by GlpP, catabolite repression via CcpA and inducer exclusion triggered by P-GlpK dephosphorylation control Bacillus subtilis glpFK expression. Mol Microbiol 43:1039-52.[PMID:11929549]
PubMed search
Ortholog SSDB     COG
Paralog SSDB
Motif SSDB
Localization PSORT   SOSUI